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As early as the 1930s, experiments were done in which these tars were painted on the ear linings of rabbits or the shaved backs of mice and found to cause tumors

For iron and zinc, In the present study, consistent with the findings of Contribution From Laboratory Air, Analytical Equipment or Analytical Reagents Given the very low levels of many of the toxicants that are now measured in e-cigarette aerosols, combined with the relatively large numbers of puffs taken on e-cigarettes in comparison to tobacco cigarettes, it is essential to understand the contribution to measured values from environmental factors

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