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Concerning abstinence thresholds, eleven [16, 17, 25, 26, 29, 30, 33, 35, 38,39,40] of the 30 trials do not define these abstinence thresholds
[10] Nevertheless nicotine has a relatively high toxicity in comparison to many other alkaloids such as caffeine, which has an LD 50 of 127 mg/kg when administered to mice
It had to stop.' Ronnie eventually went to rehab and spent several years trying to put an end to his addiction before he eventually got clean in 2010 at the age of 63
![YTP] 500 cigarettes written by someone who smoked 500 cigarettes](https://i.ytimg.com/vi/cqCfq3Y56Q8/hq720.jpg?sqp=-oaymwE7CK4FEIIDSFryq4qpAy0IARUAAAAAGAElAADIQj0AgKJD8AEB-AH-CYAC0AWKAgwIABABGHIgWShAMA8=&rs=AOn4CLAikNXki_2sSMxPJMu9roKRQ2v52Q)
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