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To assess which of these factors can be considered true confounding factors and should be included in the analysis, a directed acyclic graph (DAG) 12 was developed as illustrated in Figure 1

Most hotels will also have designated smoking areas around the outside of the hotel or in an outside bar area

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Instead of offering new ways of delivering nicotine to addicted smokers, we offer smokers in the form that they are used to, the option to take control of their nicotine consumption and make informed and more productive choices, including the choice to avoid addictive levels of nicotine altogether