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The implementation used the R package netmeta and specifically used the function netmetabin. 43 RESULTS Efficacy Analyses Continuous smoking abstinence rate Weeks 9-12 (unadjusted): For the continuous smoking abstinence rate Weeks 9-12 outcome, ORs (95% CI) for cytisinicline vs varenicline ranged from 1.30 (0.83-2.02) for inverse variance to 1.32 (0.87-2.02) for Mantel-Haenszel, with no significant differences ( Table 2 )

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