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It is highly toxic when ingested or absorbed in high doses (beyond those typically found in regulated cigarettes, e-vapor, or oral smokeless products)

Rahman MS, Reza AHMS, Siddique MAB, Akbor MA, Hasan M (2023) Accumulation of arsenic and other metals in soil and human consumable foods of Meherpur district, southwestern Bangladesh, and associated health risk assessment

In 2023, those top ten e-cigarette manufacturers collectively hold a significant share of 43.0% in the global e-cigarette market