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Competing interests Saoirse Elizabeth OSullivan is a paid consultant to Vectura Fertin Pharma, Switzerland, and a paid employee of Artelo Biosceince, USA

Because the baseline incidence of lung cancer in the population is so small, the researchers conducted a case-control study to ensure they would have both patients with and without lung cancer in their study (matched by age and economic status)

This condition is characterized by wrinkling and discoloration of the lips and mouth

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