Three systematic reviews and meta-analyses, incorporating data from 21, 15, and 8 studies respectively, provided evidence supporting a correlation between SHS exposure and the risk of COPD, with relative risks of 1.44 (95% CI 0.67 to 3.12), 2.02 (95% CI 1.52 to 2.67), and 1.66 (95% CI 1.38 to 2.00), respectively 14,51,52
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