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All deaths annually attributable to alcohol, illicit drug use, human immunodeficiency disease, homicides, suicides, and car accidents combined do not equal the number caused annually by cigarette smoking

Inflammation increases oxidative stress, causing fatigue

Stay Active: Play winter games such as walking or ice skating to refocus your mind and also exercise

However, there were significant disparities between British nations: this prevalence would have fallen by two thirds in Wales, from 23 % to 8 %, while it would have remained fairly stable in England (16.2 % to 14.2 %) and, to a lesser extent, in Scotland (12 % to 11.3 %)