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The reductions in prevalence observed in Brazil have been attributed to important regulatory measures implemented by the country over the past few decades, and, especially after the ratification of the WHO Framework Convention on Tobacco Control(FCTC) in 2005.31 These measures included a national ban on tobacco advertising, a national comprehensive smoke-free policy, large pictorial health warnings on cigarette packages, and continuous raises in taxes and prices of tobacco products

Cigarette smoking during pregnancy regulates the expression of specific nicotinic acetylcholine receptor (nAChR) subunits in the human placenta

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