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[3] This species was preferable to the native Nicotiana rustica , which was harsher
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Within about 10 seconds, the bloodstream carries a stimulant called nicotine to the brain, triggering the release of dopamine and other neurotransmitters, including endorphins, that create the pleasurable sensations which make smoking highly addictive
However, the PHE review of 2018 contradicts these arguments in unequivocal terms, stating that, evidence does not support the concern that e-cigarettes are a route into smoking among young people (youth smoking rates in the UK continue to decline, regular use is rare and is almost entirely confined to those who have smoked). Can vaping help you stop smoking
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