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[2] Now, after many years of state and local action to again raise the age to 21, a nationwide standard of 21 as the minimum legal sale age for all tobacco products, including e-cigarettes, has been enacted

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The current findings of markedly faster BNA in women than men after smoke inhalation and the correlations between the rates of BNA with ratings of some important aspects of smoking motivation may suggest a neuropharmacological mechanism underlying the sex differences in the reinforcement of nicotine/smoking

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