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The drive toward lower-risk products in the tobacco industry has opened up the field to a set of new players, many of which have already made names for themselves

The test has gone through several iterations since its introduction, but it remains in use to this day, and is still one of the main ways of assessing addiction

First, given that the aim of cMRTPs is to replace cigarettes, studies should always compare the effects of a cMRTP with those caused by cigarettes and, whenever possible, use smoking cessation as the benchmark as outlined previously [6]