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Researchproven as an effective public health intervention, the campaign is credited with keeping hundreds of thousands of teens from starting to smoke

"Both smoking and HPV are associated with heightened oxidative stress and DNA damage, which are factors in cancer, and according to previous research, can regulate superoxide dismutase 2 [SOD2], a putative biomarker of oral cancer malignancy and other diseases associated with HPV." The researchers began by analyzing oral cells that contained the oncoproteins HPV16 E6 and E7 [indicating HPV infection] and were exposed to cigarette smoke condensate in vitro

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In 2000, one in five cigarettes smoked in the UK were illicit