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This is known as idiopathic costochondritis, and while the exact reason is unclear, it is believed to be related to the bodys immune response or a disruption in the normal function of the cartilage

Food and Drugs Administration (FDA) also said, "the toxic mix of chemicalsnot nicotinecauses the serious health effects among those who use tobacco products, including fatal lung diseases, like chronic obstructive pulmonary disease (COPD) and cancer. These toxic substances (carbon monoxide, formaldehyde, ammonia, hydrogen cyanide, arsenic, DDT, etc.) are produced by the burning of dried tobacco leaf and are subsequently inhaled by the smoker

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It is characterized by chronic inflammation of the airways, lung tissue, and pulmonary blood vessels