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This question What is the healthiest thing to smoke? often arises among smokers looking to minimize harm

This is a vital difference, as it means that vapes can still appeal to adults as a tool to stop smoking, particularly because our previous research has established vaping is significantly less harmful than smoking. The authors said their study also found that a greater proportion of teenagers who had never smoked or vaped perceived no interest among people their age in trying any of the products shown in plain white or green packaging, suggesting that removing brand imagery could deter teenagers from taking up vaping in the first place

However, in vitro cytotoxicity assays are useful in determining the contribution of different tobacco blends or cigarette components (e.g., the filter) to the overall cytotoxicity of the smoke and in identifying causative cytotoxic agents in smoke and mechanistic pathways