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NHS England Digital
The difference between the total number of electronic nicotine delivery system applications made (26.64 million) and the various ways in which applications are resolved (refuse to accept, refuse to file, marketing denial order, marketing granted order, withdrawal by applicant, and closure) stood at 497,000 applications unaccounted for in March 2025
UCL News reports that in a series of small studies, people who switched from cigarettes to heated tobacco had lower levels of exposure to harmful chemicals
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