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51 After adjustment for multiple potential confounders, such as race, education, current alcohol consumption, exercise, aspirin use, body mass index, and dietary fat consumption, Henley and colleagues 51 found spit tobacco use in CPS-I and CPS-II was associated with an increased hazard ratio for mortality due to cerebrovascular disease (Table 6)

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Prenatal Substance Exposure and Birth Weight: Findings From the HEALthy Brain and Child Development Study Gretchen Bandoli, Catherine Psaras, Ludmila N