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The PACT Act also generally prohibits mailing ENDS through the United States Postal Service (USPS)

Effects of Cigarette Smoke Exposure on Innate Immunity The innate defense mechanisms of the airways and lungs encompass structural components, cough reflex, mucociliary clearance, epithelial barrier, humoral factors (surfactant proteins, complement proteins, antimicrobial peptides), and cells that elicit immune responses (epithelial cells, macrophages, monocytes, dendritic cells, neutrophils, natural killer cells, and mast cells)

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