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Read these publications from Philip Morris International (PMI) scientists about biomarkers of exposure for nicotine and other chemicals: Assessment of the reduction in levels of exposure to harmful and potentially harmful constituents in Japanese subjects using a novel tobacco heating system compared with conventional cigarettes and smoking abstinence: A randomized controlled study in confinement Effects of Switching to the Tobacco Heating System 2.2 Menthol, Smoking Abstinence, or Continued Cigarette Smoking on Biomarkers of Exposure: A Randomized, Controlled, Open-Label, Multicenter Study in Sequential Confinement and Ambulatory Settings (Part 1) Pharmacokinetic (PK) studies observe the levels of nicotine in the blood over time, along with its metabolization and elimination from the body

could do something similar with cigarette boxes too which would be fitting for at PARC

People who are married to smokers have a much higher risk of getting lung cancer and heart disease

White, which was ranked the least harmful color descriptor in the current study, has been found to be perceived as having lower tar and may be chosen over other colors by smokers concerned about health 15