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Serious reported side effects include: Heart chest pain fast and irregular heartbeat hypertension (raised blood pressure) Lungs breathing difficulties Kidneys acute kidney injury Brain seizures stroke Psychological agitation, anxiety and paranoia aggressive and violent behaviour psychosis Other severe hyperthermia breakdown of muscle tissue (rhabdomyolysis) vomiting

Mattison and John Schneider Coronet Magazine May 1950 Although the authors of this article downplay, deride, or debunk the increasing number of medical reports of a variety of adverse health effects caused by smoking, Coronet , a general interest, family-oriented magazine similar in format to Readers Digest (which in 1952 became the first major magazine to warn regularly about the dangers of smoking) did not have cigarette advertising

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