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In addition, avoiding direct comparison between the harms of traditional cigarettes and ENDS is recommended due to existing uncertainties, in particular those related to the high prevalence of dual or multiple product use, the variability of types/generations of ENDS and in their levels of nicotine content, and to a lack of rigourous and standardised comparative studies

That meant that he was still around to create more cigars and celebrate the companys 10th anniversary, which came with a new cigar, the Epic Ten

Adolescents exposed to nicotine in particular showed enhanced vulnerability to impulsivity and mood disorders, among other issues

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