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Keywords: E-cigarette and asthma, E-liquid and asthma, Asthma, E-cigarette flavorings, E-cigarette and inflammation, Allergy Introduction Smoking has devastating effects on human health, and while nearly 18% of all adults in the USA currently smoke, tobacco use among adults and high school students is declining [14] due to FDA-imposed regulations on the sale, distribution, advertising, and promotion of tobacco products [57]